FOXL2 antibody (pSer263)

Catalog No. ABIN1531739

The Rabbit Polyclonal anti-FOXL2 antibody is suitable to detect FOXL2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for FOXL2 antibody (pSer263) (ABIN1531739)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOXL2 Antibody

Binding Specificity: AA 229-278, pSer263

Purpose: FoxL2 (phospho Ser263) Antibody

Specificity: Phospho-FoxL2 (S263) Polyclonal Antibody detects endogenous levels of FoxL2 protein only when phosphorylated at S263.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FOXL2 around the phosphorylation site of Ser263. AA range:229-278

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Alternative Name: FOXL2

Background:

Synonyms: FOXL2, Forkhead box protein L2

Background: This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Expansion of a polyalanine repeat region and other mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. [provided by RefSeq, Jul 2016],

Gene Name: FOXL2

Protein Name: Forkhead box protein L2

Molecular Weight: 38 kDa

Gene ID: 668

OMIM: 110100

UniProt: P58012

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity