BLK antibody (pTyr501)

Catalog No. ABIN1532037

This Rabbit Polyclonal antibody specifically detects BLK in ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BLK antibody (pTyr501) (ABIN1532037)

Target: BLK (B Lymphoid Tyrosine Kinase (BLK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLK antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-BLK Antibody

Binding Specificity: AA 456-505, pTyr501

Specificity:

BLK (Phospho-Tyr501) Antibody detects endogenous levels of BLK only when phosphorylated at Tyr501.

PhosphorylationH:Y501 M:Y495 R:Y495

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human BLK around the phosphorylation site of Tyr501.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.146591 (NCBI Gene Symbol: BLK)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for BLK

Target: BLK (B Lymphoid Tyrosine Kinase (BLK))

Alternative Name: BLK

Background:

Synonyms: B lymphocyte kinase, p55-BLK

NCBI Gene Symbol: BLK

Molecular Weight: 57 kDa

Gene ID: 640

OMIM: 191305

UniProt: P51451

Pathways: Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling