ICK antibody (pTyr159)

Catalog No. ABIN1532046

This Rabbit Polyclonal antibody specifically detects ICK in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ICK antibody (pTyr159) (ABIN1532046)

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-ICK Antibody

Binding Specificity: AA 125-174, pTyr159

Purpose: Intestinal Cell Kinase (phospho Tyr159) Antibody

Specificity: Phospho-Intestinal Cell Kinase (Y159) Polyclonal Antibody detects endogenous levels of Intestinal Cell Kinase protein only when phosphorylated at Y159.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ICK around the phosphorylation site of Tyr159. AA range:125-174

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ICK

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Alternative Name: ICK

Background:

Synonyms: ICK, KIAA0936, Serine/threonine-protein kinase ICK, Intestinal cell kinase, hICK, Laryngeal cancer kinase 2, LCK2, MAK-related kinase, MRK

Background: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases.This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008],

Gene Name: ICK

Protein Name: Serine/threonine-protein kinase ICK

Molecular Weight: 71 kDa

Gene ID: 22858

OMIM: 612325

UniProt: Q9UPZ9