MSK2 antibody (pThr568)

Catalog No. ABIN1532065

The Rabbit Polyclonal anti-MSK2 antibody is suitable to detect MSK2 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for MSK2 antibody (pThr568) (ABIN1532065)

Target: MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MSK2 Antibody

Binding Specificity: AA 531-580, pThr568

Purpose: MSK2 (phospho Thr568) Antibody

Specificity: Phospho-MSK2 (T568) Polyclonal Antibody detects endogenous levels of MSK2 protein only when phosphorylated at T568.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MSK2 around the phosphorylation site of Thr568. AA range:531-580

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MSK2

Target: MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))

Alternative Name: MSK2

Background:

Synonyms: RPS6KA4, MSK2, Ribosomal protein S6 kinase alpha-4, S6K-alpha-4, 90 kDa ribosomal protein S6 kinase 4, Nuclear mitogen- and stress-activated protein kinase 2, Ribosomal protein kinase B, RSKB

Background: ribosomal protein S6 kinase A4(RPS6KA4) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016],

Gene Name: RPS6KA4

Protein Name: Ribosomal protein S6 kinase alpha-4

Molecular Weight: 85 kDa

Gene ID: 8986

OMIM: 603606

UniProt: O75676