PKC beta antibody (pSer661)

Catalog No. ABIN1532073

This Rabbit Polyclonal antibody specifically detects PKC beta in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for PKC beta antibody (pSer661) (ABIN1532073)

Target: PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKC beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PKC beta Antibody

Binding Specificity: AA 622-671, pSer661

Specificity:

PKCB (Phospho-Ser661) Antibody detects endogenous levels of PKCB only when phosphorylated at Ser661.

PhosphorylationH:S661 M:S629 R:S661

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PKCB around the phosphorylation site of Ser661.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:20000

Comment:

Unigene-Number: Hs.460355 (NCBI Gene Symbol: PRKCB)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PKC beta

Target: PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

Alternative Name: PKCB

Background:

Synonyms: kinase PKC-beta, KPCB, PKC II, PKC-B, PKC-beta, PKC-II, PRKCB, PRKCB1, Protein kinase C, beta type

NCBI Gene Symbol: PRKCB

Molecular Weight: 76 kDa

Gene ID: 5579

OMIM: 176970

UniProt: P05771

Pathways: WNT Signaling, TCR Signaling, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded Protein Response, BCR Signaling