RSK1/2/3/4 (AA 191-240), (pSer221) antibody
Quick Overview for RSK1/2/3/4 (AA 191-240), (pSer221) antibody (ABIN1532079)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 191-240, pSer221
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Specificity
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RSK1/2/3/4 (Phospho-Ser221/227/S218/232) Antibody detects endogenous levels of RSK1/2/3/4 only when phosphorylated at Ser221/227/S218/232.
PhosphorylationH:S221/227/S218/232 M:S221/227/S218/252
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Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Purity
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human RSK1/2/3/4 around the phosphorylation site of Ser221/227/S218/232.
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Isotype
- IgG
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Application Notes
- WB: 1:500~1:1000 ELISA: 1:40000
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Comment
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Unigene-Number: Hs.149957, Hs.445387, Hs.655277, Hs.368153 (NCBI Gene Symbol: RPS6KA1)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable at -20°C for at least 1 year.
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Expiry Date
- 12 months
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- RSK1/2/3/4
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Background
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Synonyms: S6K-alpha 1, 90 kDa ribosomal protein S6 kinase 1, p90-RSK 1, Ribosomal S6 kinase 1, RSK-1, pp90RSK1, p90S6K, MAP kinase-activated protein kinase 1a, MAPKAPK1A/ S6K-alpha 3, 90 kDa ribosomal protein S6 kinase 3, p90-RSK 3, Ribosomal S6 kinase 2, RSK-2, pp
NCBI Gene Symbol: RPS6KA1
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Molecular Weight
- 82 kDa
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Gene ID
- 6195, 6197, 6196
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OMIM
- 601684
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UniProt
- Q15418, P51812, Q15349, Q9UK32
Target
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