IRF3 antibody (pSer386)

Catalog No. ABIN1532087

This anti-IRF3 antibody is a Rabbit Polyclonal antibody detecting IRF3 in WB and ELISA. Suitable for Human.

Quick Overview for IRF3 antibody (pSer386) (ABIN1532087)

Target: IRF3 (Interferon Regulatory Factor 3 (IRF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IRF3 Antibody

Binding Specificity: AA 352-401, pSer386

Specificity:

IRF-3 (Phospho-Ser386) Antibody detects endogenous levels of IRF-3 only when phosphorylated at Ser386.

PhosphorylationH:S386

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IRF-3 around the phosphorylation site of Ser386.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:1000

Comment:

Unigene-Number: Hs.75254 (NCBI Gene Symbol: IRF3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for IRF3

Target: IRF3 (Interferon Regulatory Factor 3 (IRF3))

Alternative Name: IRF-3

Background:

Synonyms: Interferon regulatory factor 3, IRF3

NCBI Gene Symbol: IRF3

Molecular Weight: 47 kDa

Gene ID: 3661

OMIM: 603734

UniProt: Q14653

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades