Caveolin 2 antibody (pTyr27)

Catalog No. ABIN1532114

The Rabbit Polyclonal anti-Caveolin 2 antibody (ABIN1532114) specifically detects Caveolin 2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Caveolin 2 antibody (pTyr27) (ABIN1532114)

Target: Caveolin 2 (CAV2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Caveolin 2 Antibody

Binding Specificity: AA 12-61, pTyr27

Purpose: Caveolin-2 (phospho Tyr27) Antibody

Specificity: Phospho-Caveolin-2 (Y27) Polyclonal Antibody detects endogenous levels of Caveolin-2 protein only when phosphorylated at Y27.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Caveolin 2 around the phosphorylation site of Tyr27. AA range:12-61

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Caveolin 2

Target: Caveolin 2 (CAV2)

Alternative Name: Caveolin 2

Background:

Synonyms: CAV2, Caveolin-2

Background: The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011],

Gene Name: CAV2

Protein Name: Caveolin-2

Molecular Weight: 18 kDa

Gene ID: 858

OMIM: 601048

UniProt: P51636

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development