ATR antibody (pSer428)

Catalog No. ABIN1532115

This Rabbit Polyclonal antibody specifically detects ATR in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for ATR antibody (pSer428) (ABIN1532115)

Target: ATR (ATR serine/threonine kinase (ATR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATR antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ATR Antibody

Binding Specificity: AA 394-443, pSer428

Specificity:

ATR (Phospho-Ser428) Antibody detects endogenous levels of ATR only when phosphorylated at Ser428.

PhosphorylationH:S428

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ATR around the phosphorylation site of Ser428.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.271791 (NCBI Gene Symbol: ATR)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for ATR

Target: ATR (ATR serine/threonine kinase (ATR))

Alternative Name: ATR

Background:

Synonyms: ataxia telangiectasia and Rad3-related protein, FRAP-related protein, FRP1, kinase ATR, protein kinase ATR

NCBI Gene Symbol: ATR

Molecular Weight: 301 kDa

Gene ID: 545

OMIM: 210600

UniProt: Q13535

Pathways: Positive Regulation of Response to DNA Damage Stimulus