GAB2 antibody (GRB2-Associated Binding Protein 2) (AA 609-658)

Details for Product anti-GAB2 Antibody No. ABIN1532144, Supplier: Log in to see
Antigen
  • GAB2
  • AI463667
  • D130058I17Rik
  • p97
  • GRB2 associated binding protein 2
  • GRB2-associated binding protein 2
  • growth factor receptor bound protein 2-associated protein 2
  • GAB2
  • gab2
  • Gab2
Alternatives
anti-Human GAB2 antibody for Western Blotting
Epitope
AA 609-658, pTyr643
31
26
25
22
15
15
15
12
11
5
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
210
162
151
3
3
1
1
1
1
1
1
Host
Rabbit
194
17
1
Clonality
Polyclonal
Conjugate
This GAB2 antibody is un-conjugated
7
7
7
5
5
5
5
5
5
5
5
5
5
5
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
145
89
65
47
30
7
2
2
1
1
Options
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Immunogen The antiserum was produced against synthesized peptide derived from human Gab2 around the phosphorylation site of Tyr643.
Isotype IgG
Specificity

Gab2 (Phospho-Tyr643) Antibody detects endogenous levels of Gab2 only when phosphorylated at Tyr643.

PhosphorylationH:Y643 M:Y632 R:Y632

Purification The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Purity > 95 %
Plasmids, Primers & others Plasmids, Primers & others GAB2 products on genomics-online (e.g. as negative or positive controls)
Antigen GRB2-Associated Binding Protein 2 (GAB2)
Alternative Name Gab2 (GAB2 Antibody Abstract)
Background

Synonyms: GRB2-associated-binding protein 2, Growth factor receptor bound protein 2-associated protein 2, GRB2-associated binder 2, pp100, KIAA0571

NCBI Gene Symbol: GAB2

Molecular Weight 74 kDa
Gene ID 9846
OMIM 606203
UniProt Q9UQC2
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Application Notes WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000
Comment

Unigene-Number: Hs.429434 (NCBI Gene Symbol: GAB2)

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20°C for at least 1 year.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 609-658), (pTyr643) antibody (ABIN1532144) Western blot analysis of extracts from Jurkat cells treated with IFN 2500U/ML 30', us...
Immunohistochemistry (IHC) image for anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 609-658), (pTyr643) antibody (ABIN1532144) Immunohistochemistry analysis of paraffin-embedded human brain, using Gab2 (Phospho-T...
Background publications Nishida, Yoshida, Itoh, Fukada, Ohtani, Shirogane, Atsumi, Takahashi-Tezuka, Ishihara, Hibi, Hirano: "Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors." in: Blood, Vol. 93, Issue 6, pp. 1809-16, 1999 (PubMed).

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