MYB antibody (pSer532)

Catalog No. ABIN1532156

The Rabbit Polyclonal anti-MYB antibody (ABIN1532156) specifically detects MYB in IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for MYB antibody (pSer532) (ABIN1532156)

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYB antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-MYB Antibody

Binding Specificity: AA 496-545, pSer532

Purpose: c-Myb (phospho Ser532) Antibody

Specificity: Phospho-c-Myb (S532) Polyclonal Antibody detects endogenous levels of c-Myb protein only when phosphorylated at S532.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Myb around the phosphorylation site of Ser532. AA range:496-545

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Alternative Name: Myb

Background:

Synonyms: MYB, Transcriptional activator Myb, Proto-oncogene c-Myb

Background: This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

Gene Name: MYB

Protein Name: Transcriptional activator Myb

Molecular Weight: 72 kDa

Gene ID: 4602

OMIM: 189990

UniProt: P10242

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process