GRF2 antibody (AA 470-519)

Catalog No. ABIN1532724

This Rabbit Polyclonal antibody specifically detects GRF2 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for GRF2 antibody (AA 470-519) (ABIN1532724)

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRF2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-GRF2 Antibody

Binding Specificity: AA 470-519

Specificity:

RapGEF1 Antibody detects endogenous levels of total RapGEF1 protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RAPGEF1.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.127897 (NCBI Gene Symbol: RAPGEF1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for GRF2

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Alternative Name: RapGEF1

Background:

Synonyms: C3G, CRK SH3-binding GNRP, GRF2, RPGF1, Rap guanine nucleotide exchange factor 1, guanine nucleotide-releasing factor 2

NCBI Gene Symbol: RAPGEF1

Molecular Weight: 120 kDa

Gene ID: 2889

OMIM: 600303

UniProt: Q13905

Pathways: Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor