CaMKIIalpha/delta antibody (AA 256-305)

Catalog No. ABIN1532822

The Rabbit Polyclonal anti-CaMKIIalpha/delta antibody (ABIN1532822) specifically detects CaMKIIalpha/delta in IF, WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CaMKIIalpha/delta antibody (AA 256-305) (ABIN1532822)

Target: CaMKIIalpha/delta (CaMK2 a/d) (Calcium/calmodulin-Dependent Protein Kinase II (CaMK2 a/d))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CaMKIIalpha/delta antibody is un-conjugated

Application: Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CaMKIIalpha/delta Antibody

Binding Specificity: AA 256-305

Purpose: CaMKIIα/δ Antibody

Specificity: CaMKIIα/δ Polyclonal Antibody detects endogenous levels of CaMKIIα/δ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/delta. AA range:256-305

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CaMKIIalpha/delta

Target: CaMKIIalpha/delta (CaMK2 a/d) (Calcium/calmodulin-Dependent Protein Kinase II (CaMK2 a/d))

Alternative Name: CaMK2 alpha/delta

Background:

Synonyms: CAMK2A, CAMKA, KIAA0968, Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2D, CAMKD, Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II

Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],

Gene Name: CAMK2A/CAMK2D

Protein Name: Calcium/calmodulin-dependent protein kinase type II subunit alpha/delta

Molecular Weight: 54 kDa

Gene ID: 815, 817

OMIM: 114078

UniProt: Q9UQM7