Cullin 3 antibody (AA 1-50)

Catalog No. ABIN1533246

The Rabbit Polyclonal anti-Cullin 3 antibody is suitable to detect Cullin 3 in samples from Human and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for Cullin 3 antibody (AA 1-50) (ABIN1533246)

Target: Cullin 3 (CUL3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Cullin 3 Antibody

Binding Specificity: AA 1-50

Purpose: CUL-3 Antibody

Specificity: CUL-3 Polyclonal Antibody detects endogenous levels of CUL-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Cullin 3. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:5000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cullin 3

Target: Cullin 3 (CUL3)

Alternative Name: Cullin 3

Background:

Synonyms: CUL3, KIAA0617, Cullin-3, CUL-3

Background: This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],

Gene Name: CUL3

Protein Name: Cullin-3

Molecular Weight: 88 kDa

Gene ID: 8452

OMIM: 603136

UniProt: Q13618

Pathways: M Phase