FGFR3 antibody (AA 131-180)

Catalog No. ABIN1533273

The Rabbit Polyclonal anti-FGFR3 antibody has been validated for WB, ELISA and IHC. It is suitable to detect FGFR3 in samples from Human, Mouse and Rat. There is 1 publication available.

Quick Overview for FGFR3 antibody (AA 131-180) (ABIN1533273)

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFR3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FGFR3 Antibody

Binding Specificity: AA 131-180

Specificity:

FGFR3 Antibody detects endogenous levels of total FGFR3 protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FGFR3.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.1420 (NCBI Gene Symbol: FGFR3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

References for anti-FGFR3 antibody (ABIN1533273)

Shimizu, Ishikawa, Iwai, Ueki, Sugihara, Onishi, Kuninaka, Miyamoto, Toyama, Ijiri, Mori, Matsuzaki, Yaguchi, Nishio, Kawakami, Ikeda, Saya: "Fibroblast growth factor-2 (Fgf2) is an important factor that maintains cellular immaturity and contributes to aggressiveness of osteosarcoma." in: Molecular cancer research : MCR, (2012) (PubMed).

Target Details for FGFR3

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Alternative Name: FGFR3

Background:

Synonyms: FGFR-3, CD333 antigen, Fibroblast growth factor receptor 3, JTK4, CD333

NCBI Gene Symbol: FGFR3

Molecular Weight: 87 kDa

Gene ID: 2261

OMIM: 134934

UniProt: P22607

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding