GUCYB antibody (AA 10-59)

Catalog No. ABIN1533300

The Rabbit Polyclonal anti-GUCYB antibody is suitable to detect GUCYB in samples from Human, Mouse and Rat. It has been validated for IHC, WB, ELISA and IF.

Quick Overview for GUCYB antibody (AA 10-59) (ABIN1533300)

Target: GUCYB (Guanylate Cyclase, beta (GUCYB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCYB antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-GUCYB Antibody

Binding Specificity: AA 10-59

Purpose: GCS-β-1 Antibody

Specificity: GCS-β-1 Polyclonal Antibody detects endogenous levels of GCS-β-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Guanylate Cyclase beta. AA range:10-59

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GUCYB

Target: GUCYB (Guanylate Cyclase, beta (GUCYB))

Alternative Name: Guanylate Cyclase beta

Background:

Synonyms: GUCY1B3, GUC1B3, GUCSB3, GUCY1B1, Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit

Background: This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

Gene Name: GUCY1B3

Protein Name: Guanylate cyclase soluble subunit beta-1

Molecular Weight: 70 kDa

Gene ID: 2983

OMIM: 139397

UniProt: Q02153