PRAF2 antibody (AA 129-178)

Catalog No. ABIN1533318

The Rabbit Polyclonal anti-PRAF2 antibody is suitable to detect PRAF2 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for PRAF2 antibody (AA 129-178) (ABIN1533318)

Target: PRAF2 (PRA1 Domain Family, Member 2 (PRAF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRAF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PRAF2 Antibody

Binding Specificity: AA 129-178

Purpose: PRAF2 Antibody

Specificity: PRAF2 Polyclonal Antibody detects endogenous levels of PRAF2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human JM4. AA range:129-178

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PRAF2

Target: PRAF2 (PRA1 Domain Family, Member 2 (PRAF2))

Alternative Name: JM4

Background:

Synonyms: PRAF2, JM4, PRA1 family protein 2

Background: function:May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.,similarity:Belongs to the PRA1 family.,subunit:Interacts with CCR5 and GDE1.,tissue specificity:Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non-neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.,

Gene Name: PRAF2

Protein Name: PRA1 family protein 2

Molecular Weight: 19 kDa

Gene ID: 11230

UniProt: O60831

Pathways: Dicarboxylic Acid Transport