MMP15 antibody (AA 611-660)

Catalog No. ABIN1533347

This Rabbit Polyclonal antibody specifically detects MMP15 in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for MMP15 antibody (AA 611-660) (ABIN1533347)

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP15 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MMP15 Antibody

Binding Specificity: AA 611-660

Purpose: MMP-15 Antibody

Specificity: MMP-15 Polyclonal Antibody detects endogenous levels of MMP-15 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-15. AA range:611-660

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MMP15

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Alternative Name: MMP-15

Background:

Synonyms: MMP15, Matrix metalloproteinase-15, MMP-15, Membrane-type matrix metalloproteinase 2, MT-MMP 2, MTMMP2, Membrane-type-2 matrix metalloproteinase, MT2-MMP, MT2MMP, SMCP-2

Background: This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016],

Gene Name: MMP15

Protein Name: Matrix metalloproteinase-15

Molecular Weight: 75 kDa

Gene ID: 4324

OMIM: 602261

UniProt: P51511