TYR antibody (AA 471-520)

Catalog No. ABIN1533452

The Rabbit Polyclonal anti-TYR antibody (ABIN1533452) specifically detects TYR in WB and ELISA. The antibody is reactive with Human and Monkey samples.

Quick Overview for TYR antibody (AA 471-520) (ABIN1533452)

Target: TYR (Tyrosinase (TYR))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TYR Antibody

Binding Specificity: AA 471-520

Purpose: TYR Antibody

Specificity: TYR Polyclonal Antibody detects endogenous levels of TYR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Tyrosinase. AA range:471-520

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Alternative Name: Tyrosinase

Background:

Synonyms: TYR; Tyrosinase; LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen AB

Background: tyrosinase(TYR) Homo sapiens The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008],

Gene Name: TYR

Protein Name: Tyrosinase

Molecular Weight: 60 kDa

Gene ID: 7299

OMIM: 103470

UniProt: P14679