Urocortin antibody (AA 71-120)

Catalog No. ABIN1533456

This Rabbit Polyclonal antibody specifically detects Urocortin in IHC, ELISA and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Urocortin antibody (AA 71-120) (ABIN1533456)

Target: Urocortin (UCN)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Urocortin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Urocortin Antibody

Binding Specificity: AA 71-120

Purpose: Urocortin Antibody

Specificity: Urocortin Polyclonal Antibody detects endogenous levels of Urocortin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Urocortin. AA range:71-120

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Urocortin

Target: Urocortin (UCN)

Alternative Name: Urocortin

Background:

Synonyms: UCN, Urocortin

Background: This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family. The encoded preproprotein is proteolytically processed to generate the mature peptide, an endogenous ligand for both corticotropin-releasing factor receptor 1 and corticotropin-releasing factor receptor 2. In the brain this peptide may be responsible for the effects of stress on appetite. This peptide may also play a role in mood disorders, neurodegeneration, and skeletal system disorders. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin-2. [provided by RefSeq, Feb 2016],

Gene Name: UCN

Protein Name: Urocortin

Molecular Weight: 13 kDa

Gene ID: 7349

OMIM: 600945

UniProt: P55089

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of Cell Size, Feeding Behaviour