DIRC2 antibody (AA 261-310)

Catalog No. ABIN1533467

The Rabbit Polyclonal anti-DIRC2 antibody (ABIN1533467) specifically detects DIRC2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DIRC2 antibody (AA 261-310) (ABIN1533467)

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIRC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DIRC2 Antibody

Binding Specificity: AA 261-310

Purpose: XRCC4 Antibody

Specificity: XRCC4 Polyclonal Antibody detects endogenous levels of XRCC4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human XRCC4. AA range:261-310

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DIRC2

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Alternative Name: RCC4

Background:

Synonyms: XRCC4, DNA repair protein XRCC4, X-ray repair cross-complementing protein 4

Background: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015],

Gene Name: XRCC4

Protein Name: DNA repair protein XRCC4

Molecular Weight: 38 kDa

Gene ID: 7518

OMIM: 194363

UniProt: Q13426