GAK antibody (AA 101-150)

Catalog No. ABIN1533492

This Rabbit Polyclonal antibody specifically detects GAK in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for GAK antibody (AA 101-150) (ABIN1533492)

Target: GAK (Cyclin G Associated Kinase (GAK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GAK Antibody

Binding Specificity: AA 101-150

Purpose: GAK Antibody

Specificity: GAK Polyclonal Antibody detects endogenous levels of GAK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GAK. AA range:101-150

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GAK

Target: GAK (Cyclin G Associated Kinase (GAK))

Alternative Name: GAK

Background:

Synonyms: GAK; Cyclin-G-associated kinase

Background: cyclin G associated kinase(GAK) Homo sapiens In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],

Gene Name: GAK

Protein Name: Cyclin-G-associated kinase

Molecular Weight: 143 kDa

Gene ID: 2580

OMIM: 602052

UniProt: O14976