ZEB2 antibody (AA 71-120)

Catalog No. ABIN1533518

Cited in 2+ publications. The Rabbit Polyclonal anti-ZEB2 antibody (ABIN1533518) specifically detects ZEB2 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ZEB2 antibody (AA 71-120) (ABIN1533518)

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZEB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-ZEB2 Antibody

Binding Specificity: AA 71-120

Purpose: SIP1 Antibody

Specificity: SIP1 Polyclonal Antibody detects endogenous levels of SIP1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ZEB2. AA range:71-120

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

References for anti-ZEB2 antibody (ABIN1533518)

Harada, Miyake, Kusuda, Fujisawa: "Expression of epithelial-mesenchymal transition markers in renal cell carcinoma: impact on prognostic outcomes in patients undergoing radical nephrectomy." in: BJU international, (2012) (PubMed).

Behnsawy, Miyake, Harada, Fujisawa: "Expression patterns of epithelial-mesenchymal transition markers in localized prostate cancer: significance in clinicopathological outcomes following radical prostatectomy." in: BJU international, (2012) (PubMed).

Target Details for ZEB2

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Alternative Name: ZEB2

Background:

Synonyms: ZEB2, KIAA0569, SIP1, ZFHX1B, ZFX1B, HRIHFB2411, Zinc finger E-box-binding homeobox 2, Smad-interacting protein 1, SMADIP1, Zinc finger homeobox protein 1b

Background: The protein encoded byThis gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010],

Gene Name: ZEB2

Protein Name: Zinc finger E-box-binding homeobox 2

Molecular Weight: 136 kDa

Gene ID: 9839

OMIM: 235730

UniProt: O60315

Pathways: Tube Formation