TADA2L antibody (AA 206-255)

Catalog No. ABIN1533538

The Rabbit Polyclonal anti-TADA2L antibody is suitable to detect TADA2L in samples from Human, Mouse, Rat and Monkey. It has been validated for WB and ELISA.

Quick Overview for TADA2L antibody (AA 206-255) (ABIN1533538)

Target: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TADA2L antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TADA2L Antibody

Binding Specificity: AA 206-255

Purpose: TADA2L Antibody

Specificity: TADA2L Polyclonal Antibody detects endogenous levels of TADA2L protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ADA2L. AA range:206-255

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TADA2L

Target: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Background:

Synonyms: TADA2A, TADA2L, KL04P, Transcriptional adapter 2-alpha, Transcriptional adapter 2-like, ADA2-like protein

Background: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009],

Gene Name: TADA2A

Protein Name: Transcriptional adapter 2-alpha

Molecular Weight: 51 kDa

Gene ID: 6871

OMIM: 602276

UniProt: O75478

Pathways: Chromatin Binding