MED26 antibody (AA 1-50)

Catalog No. ABIN1533563

The Rabbit Polyclonal anti-MED26 antibody (ABIN1533563) specifically detects MED26 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for MED26 antibody (AA 1-50) (ABIN1533563)

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED26 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MED26 Antibody

Binding Specificity: AA 1-50

Purpose: CRSP70 Antibody

Specificity: CRSP70 Polyclonal Antibody detects endogenous levels of CRSP70 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MED26. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MED26

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Alternative Name: MED26

Background:

Synonyms: MED26, ARC70, CRSP7, Mediator of RNA polymerase II transcription subunit 26, Activator-recruited cofactor 70 kDa component, ARC70, Cofactor required for Sp1 transcriptional activation subunit 7, CRSP complex subunit 7, Mediator complex subu

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008],

Gene Name: MED26

Protein Name: Mediator of RNA polymerase II transcription subunit 26

Molecular Weight: 65 kDa

Gene ID: 9441

OMIM: 605043

UniProt: O95402

Pathways: Regulation of Lipid Metabolism by PPARalpha