ALDOA antibody (AA 1-50)
Quick Overview for ALDOA antibody (AA 1-50) (ABIN1533584)
Target
See all ALDOA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-50
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Purpose
- Aldolase A Antibody
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Specificity
- Aldolase A Polyclonal Antibody detects endogenous levels of Aldolase A protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Purity
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human ALDOA. AA range:1-50
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Isotype
- IgG
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Application Notes
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))
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Alternative Name
- ALDOA
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Background
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Synonyms: ALDOA, ALDA, Fructose-bisphosphate aldolase A, Lung cancer antigen NY-LU-1, Muscle-type aldolase
Background: The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011],
Gene Name: ALDOA
Protein Name: Fructose-bisphosphate aldolase A
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Molecular Weight
- 39 kDa
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Gene ID
- 226
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OMIM
- 103850
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UniProt
- P04075
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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