CDK11 antibody (AA 10-59)

Catalog No. ABIN1533654

This Rabbit Polyclonal antibody specifically detects CDK11 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for CDK11 antibody (AA 10-59) (ABIN1533654)

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CDK11 Antibody

Binding Specificity: AA 10-59

Purpose: PITSLRE Antibody

Specificity: PITSLRE Polyclonal Antibody detects endogenous levels of PITSLRE protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CDC2L1. AA range:10-59

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CDK11

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Alternative Name: CDC2L1

Background:

Synonyms: CDK11B, CDC2L1, CDK11, PITSLREA, PK58, Cyclin-dependent kinase 11B, Cell division cycle 2-like protein kinase 1, CLK-1, Cell division protein kinase 11B, Galactosyltransferase-associated protein kinase p58/GTA, PITSLRE serine/threonine-prot

Background: This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],

Gene Name: CDK11B

Protein Name: Cyclin-dependent kinase 11B

Molecular Weight: 92 kDa

Gene ID: 984

OMIM: 176873

UniProt: P21127

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase