ITPKA antibody (AA 396-445)

Catalog No. ABIN1533667

The Rabbit Polyclonal anti-ITPKA antibody is suitable to detect ITPKA in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for ITPKA antibody (AA 396-445) (ABIN1533667)

Target: ITPKA (Inositol-Trisphosphate 3-Kinase A (ITPKA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPKA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ITPKA Antibody

Binding Specificity: AA 396-445

Purpose: IP3KA Antibody

Specificity: IP3KA Polyclonal Antibody detects endogenous levels of IP3KA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IP3KA. AA range:396-445

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ITPKA

Target: ITPKA (Inositol-Trisphosphate 3-Kinase A (ITPKA))

Alternative Name: IP3KA

Background:

Synonyms: ITPKA, Inositol-trisphosphate 3-kinase A, Inositol 1, 4,5-trisphosphate 3-kinase A, IP3 3-kinase A, IP3K A, InsP 3-kinase A

Background: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011],

Gene Name: ITPKA

Protein Name: Inositol-trisphosphate 3-kinase A

Molecular Weight: 51 kDa

Gene ID: 3706

OMIM: 147521

UniProt: P23677