PPIF antibody (AA 86-135)

Catalog No. ABIN1533690

This Rabbit Polyclonal antibody specifically detects PPIF in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PPIF antibody (AA 86-135) (ABIN1533690)

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PPIF Antibody

Binding Specificity: AA 86-135

Purpose: Cyclophilin F Antibody

Specificity: Cyclophilin F Polyclonal Antibody detects endogenous levels of Cyclophilin F protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PPIF. AA range:86-135

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PPIF

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Alternative Name: PPIF

Background:

Synonyms: PPIF, CYP3, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, PPIase F, Cyclophilin F, Rotamase F

Background: The protein encoded byThis gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008],

Gene Name: PPIF

Protein Name: Peptidyl-prolyl cis-trans isomerase F mitochondrial

Molecular Weight: 22 kDa

Gene ID: 10105

OMIM: 604486

UniProt: P30405

Pathways: Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity