LIMK2 antibody (AA 461-510)

Catalog No. ABIN1533779

The Rabbit Polyclonal anti-LIMK2 antibody (ABIN1533779) specifically detects LIMK2 in WB, ELISA, IF, IHC (p) and ICC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for LIMK2 antibody (AA 461-510) (ABIN1533779)

Target: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIMK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-LIMK2 Antibody

Binding Specificity: AA 461-510

Purpose: LIMK-2 Antibody

Specificity: LIMK-2 Polyclonal Antibody detects endogenous levels of LIMK-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human LIMK2. AA range:461-510

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for LIMK2

Target: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Alternative Name: LIMK2

Background:

Synonyms: LIMK2, LIM domain kinase 2, LIMK-2

Background: mitogen-activated protein kinase 3(MAPK3) Homo sapiens The protein encoded byThis gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008],

Gene Name: LIMK2

Protein Name: LIM domain kinase 2

Molecular Weight: 72 kDa

OMIM: 601988

UniProt: P53671