CTBP2 antibody (AA 396-445)

Catalog No. ABIN1533792

This Rabbit Polyclonal antibody specifically detects CTBP2 in WB, IHC, IF and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CTBP2 antibody (AA 396-445) (ABIN1533792)

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-CTBP2 Antibody

Binding Specificity: AA 396-445

Purpose: CtBP2 Antibody

Specificity: CtBP2 Polyclonal Antibody detects endogenous levels of CtBP2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CtBP2. AA range:396-445

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CTBP2

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Alternative Name: CtBP2

Background:

Synonyms: CTBP2; C-terminal-binding protein 2; CtBP2

Background: This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014],

Gene Name: CTBP2

Protein Name: C-terminal-binding protein 2

Molecular Weight: 48 kDa

Gene ID: 1488

OMIM: 602619

UniProt: P56545