ST5 antibody (AA 411-460)

Catalog No. ABIN1533807

This Rabbit Polyclonal antibody specifically detects ST5 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ST5 antibody (AA 411-460) (ABIN1533807)

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ST5 Antibody

Binding Specificity: AA 411-460

Purpose: ST5 Antibody

Specificity: ST5 Polyclonal Antibody detects endogenous levels of ST5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ST5. AA range:411-460

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Alternative Name: ST5

Background:

Synonyms: ST5, DENND2B, HTS1, Suppression of tumorigenicity 5 protein, DENN domain-containing protein 2B, HeLa tumor suppression 1

Background: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice.The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008],

Gene Name: ST5

Protein Name: Suppression of tumorigenicity 5 protein

Molecular Weight: 126 kDa

Gene ID: 6764

OMIM: 140750

UniProt: P78524