SRY antibody (AA 51-100)

Catalog No. ABIN1533837

This Rabbit Polyclonal antibody specifically detects SRY in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SRY antibody (AA 51-100) (ABIN1533837)

Target: SRY (Sex Determining Region Y (SRY))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRY antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SRY Antibody

Binding Specificity: AA 51-100

Purpose: SRY Antibody

Specificity: SRY Polyclonal Antibody detects endogenous levels of SRY protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SRY. AA range:51-100

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SRY

Target: SRY (Sex Determining Region Y (SRY))

Alternative Name: SRY

Background:

Synonyms: SRY, TDF, Sex-determining region Y protein, Testis-determining factor

Background: This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome), translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008],

Gene Name: SRY

Protein Name: Sex-determining region Y protein

Molecular Weight: 23 kDa

Gene ID: 6736

OMIM: 480000

UniProt: Q05066