SRSF5 antibody (AA 71-120)

Catalog No. ABIN1533862

The Rabbit Polyclonal anti-SRSF5 antibody is suitable to detect SRSF5 in samples from Human, Mouse and Rat. It has been validated for IHC, ELISA and IF.

Quick Overview for SRSF5 antibody (AA 71-120) (ABIN1533862)

Target: SRSF5 (serine/arginine-Rich Splicing Factor 5 (SRSF5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF5 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-SRSF5 Antibody

Binding Specificity: AA 71-120

Purpose: SRp40 Antibody

Specificity: SRp40 Polyclonal Antibody detects endogenous levels of SRp40 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SFRS5. AA range:71-120

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SRSF5

Target: SRSF5 (serine/arginine-Rich Splicing Factor 5 (SRSF5))

Alternative Name: SFRS5

Background:

Synonyms: SRSF5, HRS, SFRS5, SRP40, Serine/arginine-rich splicing factor 5, Delayed-early protein HRS, Pre-mRNA-splicing factor SRP40, Splicing factor, arginine/serine-rich 5

Background: The protein encoded byThis gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

Gene Name: SRSF5

Protein Name: Serine/arginine-rich splicing factor 5

Molecular Weight: 31 kDa

Gene ID: 6430

OMIM: 600914

UniProt: Q13243

Pathways: Ribonucleoprotein Complex Subunit Organization