KLF1 antibody (AA 291-340)

Catalog No. ABIN1533865

The Rabbit Polyclonal anti-KLF1 antibody is suitable to detect KLF1 in samples from Human, Mouse and Rat. It has been validated for ELISA, WB and IF.

Quick Overview for KLF1 antibody (AA 291-340) (ABIN1533865)

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-KLF1 Antibody

Binding Specificity: AA 291-340

Purpose: EKLF/CKLF/UKLF Antibody

Specificity: EKLF/CKLF/UKLF Polyclonal Antibody detects endogenous levels of EKLF/CKLF/UKLF protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human KLF. AA range:291-340

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for KLF1

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Alternative Name: KLF

Background:

Synonyms: KLF1, EKLF, Krueppel-like factor 1, Erythroid krueppel-like transcription factor, EKLF, KLF5, BTEB2, CKLF, IKLF, Krueppel-like factor 5, Basic transcription element-binding protein 2, BTE-binding protein 2, Colon krueppel-like factor, GC-bo

Background: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009],

Gene Name: KLF1/KLF5/KLF7

Protein Name: Krueppel-like factor 1/Krueppel-like factor 5/Krueppel-like factor 7

Molecular Weight: 38 kDa

Gene ID: 10661, 688, 8609

OMIM: 600599

UniProt: Q13351