IB2 antibody (AA 581-630)

Catalog No. ABIN1533866

The Rabbit Polyclonal anti-IB2 antibody (ABIN1533866) specifically detects IB2 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IB2 antibody (AA 581-630) (ABIN1533866)

Target: IB2 (JIP-2) (C-Jun-Amino-Terminal Kinase-Interacting Protein 2 (JIP-2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-IB2 Antibody

Binding Specificity: AA 581-630

Purpose: JIP-2 Antibody

Specificity: JIP-2 Polyclonal Antibody detects endogenous levels of JIP-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human JIP2. AA range:581-630

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IB2

Target: IB2 (JIP-2) (C-Jun-Amino-Terminal Kinase-Interacting Protein 2 (JIP-2))

Alternative Name: JIP2

Background:

Synonyms: MAPK8IP2, IB2, JIP2, PRKM8IPL, C-Jun-amino-terminal kinase-interacting protein 2, JIP-2, JNK-interacting protein 2, Islet-brain-2, IB-2, JNK MAP kinase scaffold protein 2, Mitogen-activated protein kinase 8-interacting protein 2

Background: The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. [provided by RefSeq, Feb 2014],

Gene Name: MAPK8IP2

Protein Name: C-Jun-amino-terminal kinase-interacting protein 2

Molecular Weight: 87 kDa

Gene ID: 23542

OMIM: 607755

UniProt: Q13387