CaMK2 beta/gamma antibody (AA 509-558)

Catalog No. ABIN1533873

This Rabbit Polyclonal antibody specifically detects CaMK2 beta/gamma in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CaMK2 beta/gamma antibody (AA 509-558) (ABIN1533873)

Target: CaMK2 beta/gamma

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CaMK2 beta/gamma antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-CaMK2 beta/gamma Antibody

Binding Specificity: AA 509-558

Purpose: CaMKIIβ/γ Antibody

Specificity: CaMKIIβ/γ Polyclonal Antibody detects endogenous levels of CaMKIIβ/γ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CaMK2 beta/gamma. AA range:509-558

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CaMK2 beta/gamma

Target: CaMK2 beta/gamma

Background:

Synonyms: CAMK2G, CAMK, CAMK-II, CAMKG, Calcium/calmodulin-dependent protein kinase type II subunit gamma, CaM kinase II subunit gamma, CaMK-II subunit gamma, CAMK2B, CAM2, CAMK2, CAMKB, Calcium/calmodulin-dependent protein kinase type II subunit bet

Background: The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011],

Gene Name: CAMK2B/CAMK2G

Protein Name: Calcium/calmodulin-dependent protein kinase type II subunit beta/gamma

Molecular Weight: 62 kDa

Gene ID: 818, 816

OMIM: 602123

UniProt: Q13555