HLX antibody (AA 321-370)

Catalog No. ABIN1533893

The Rabbit Polyclonal anti-HLX antibody (ABIN1533893) specifically detects HLX in WB, ELISA, IF and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HLX antibody (AA 321-370) (ABIN1533893)

Target: HLX (H2.0-Like Homeobox (HLX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-HLX Antibody

Binding Specificity: AA 321-370

Purpose: HLX1 Antibody

Specificity: HLX1 Polyclonal Antibody detects endogenous levels of HLX1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HLX1. AA range:321-370

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HLX

Target: HLX (H2.0-Like Homeobox (HLX))

Alternative Name: HLX1

Background:

Synonyms: HLX, HLX1, H2.0-like homeobox protein, Homeobox protein HB24, Homeobox protein HLX1

Background: function:Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.,sequence caution:Translation N-terminally extended.,similarity:Belongs to the H2.0 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.,

Gene Name: HLX

Protein Name: H2.0-like homeobox protein

Molecular Weight: 50 kDa

Gene ID: 3142

OMIM: 142995

UniProt: Q14774

Pathways: Positive Regulation of Immune Effector Process