SURF1 antibody (AA 171-220)

Catalog No. ABIN1533909

The Rabbit Polyclonal anti-SURF1 antibody (ABIN1533909) specifically detects SURF1 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for SURF1 antibody (AA 171-220) (ABIN1533909)

Target: SURF1 (Surfeit 1 (SURF1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SURF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-SURF1 Antibody

Binding Specificity: AA 171-220

Purpose: SURF-1 Antibody

Specificity: SURF-1 Polyclonal Antibody detects endogenous levels of SURF-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SURF1. AA range:171-220

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SURF1

Target: SURF1 (Surfeit 1 (SURF1))

Alternative Name: SURF1

Background:

Synonyms: SURF1, SURF-1, Surfeit locus protein 1

Background: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008],

Gene Name: SURF1

Protein Name: Surfeit locus protein 1

Molecular Weight: 33 kDa

Gene ID: 6834

OMIM: 185620

UniProt: Q15526

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process