SS18 antibody (AA 1-50)

Catalog No. ABIN1533910

The Rabbit Polyclonal anti-SS18 antibody is suitable to detect SS18 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for SS18 antibody (AA 1-50) (ABIN1533910)

Target: SS18 (Synovial Sarcoma Translocation, Chromosome 18 (SS18))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SS18 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-SS18 Antibody

Binding Specificity: AA 1-50

Purpose: SYT Antibody

Specificity: SYT Polyclonal Antibody detects endogenous levels of SYT protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SSXT. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SS18

Target: SS18 (Synovial Sarcoma Translocation, Chromosome 18 (SS18))

Alternative Name: SSXT

Background:

Synonyms: SS18, SSXT, SYT, Protein SSXT, Protein SYT, Synovial sarcoma translocated to X chromosome protein

Background: disease:A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X,18)(p11.2,q11.2). The translocation is specifically found in more than 80 % of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).,similarity:Belongs to the SS18 family.,tissue specificity:Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.,

Gene Name: SS18

Protein Name: Protein SSXT

Molecular Weight: 45 kDa

Gene ID: 6760

OMIM: 600192

UniProt: Q15532

Pathways: Dicarboxylic Acid Transport