TSC22D1 antibody (AA 71-120)

Catalog No. ABIN1533921

This Rabbit Polyclonal antibody specifically detects TSC22D1 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for TSC22D1 antibody (AA 71-120) (ABIN1533921)

Target: TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSC22D1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TSC22D1 Antibody

Binding Specificity: AA 71-120

Purpose: TSC-22 Antibody

Specificity: TSC-22 Polyclonal Antibody detects endogenous levels of TSC-22 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TSC22D1. AA range:71-120

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TSC22D1

Target: TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

Alternative Name: TSC22D1

Background:

Synonyms: TSC22D1, KIAA1994, TGFB1I4, TSC22, hucep-2, TSC22 domain family protein 1, Cerebral protein 2, Regulatory protein TSC-22, TGFB-stimulated clone 22 homolog, Transforming growth factor beta-1-induced transcript 4 protein

Background: This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011],

Gene Name: TSC22D1

Protein Name: TSC22 domain family protein 1

Molecular Weight: 109 kDa

Gene ID: 8848

OMIM: 607715

UniProt: Q15714