CERKL antibody (AA 341-390)

Catalog No. ABIN1533943

The Rabbit Polyclonal anti-CERKL antibody is suitable to detect CERKL in samples from Human, Mouse and Rat. It has been validated for ELISA, WB, IHC and IF.

Quick Overview for CERKL antibody (AA 341-390) (ABIN1533943)

Target: CERKL (Ceramide Kinase-Like (CERKL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CERKL antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CERKL Antibody

Binding Specificity: AA 341-390

Purpose: CERKL Antibody

Specificity: CERKL Polyclonal Antibody detects endogenous levels of CERKL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CERKL. AA range:341-390

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CERKL

Target: CERKL (Ceramide Kinase-Like (CERKL))

Alternative Name: CERKL

Background:

Synonyms: CERKL, Ceramide kinase-like protein

Background: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease.This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010],

Gene Name: CERKL

Protein Name: Ceramide kinase-like protein

Molecular Weight: 62 kDa

Gene ID: 375298

OMIM: 608380

UniProt: Q49MI3