STEAP4 antibody (AA 201-250)

Catalog No. ABIN1533956

The Rabbit Polyclonal anti-STEAP4 antibody (ABIN1533956) specifically detects STEAP4 in ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for STEAP4 antibody (AA 201-250) (ABIN1533956)

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-STEAP4 Antibody

Binding Specificity: AA 201-250

Purpose: STAMP2 Antibody

Specificity: STAMP2 Polyclonal Antibody detects endogenous levels of STAMP2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human STEAP4. AA range:201-250

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for STEAP4

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Alternative Name: STEAP4

Background:

Synonyms: STEAP4, STAMP2, TNFAIP9, Metalloreductase STEAP4, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, Tumor necrosis factor, alpha-induced protein 9

Background: STEAP4 metalloreductase(STEAP4) Homo sapiens The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011],

Gene Name: STEAP4

Protein Name: Metalloreductase STEAP4

Molecular Weight: 51 kDa

Gene ID: 79689

OMIM: 611098

UniProt: Q687X5

Pathways: Transition Metal Ion Homeostasis