MAST2 antibody (AA 1201-1250)

Catalog No. ABIN1533960

This Rabbit Polyclonal antibody specifically detects MAST2 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for MAST2 antibody (AA 1201-1250) (ABIN1533960)

Target: MAST2 (Microtubule Associated serine/threonine Kinase 2 (MAST2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAST2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-MAST2 Antibody

Binding Specificity: AA 1201-1250

Purpose: MAST205 Antibody

Specificity: MAST205 Polyclonal Antibody detects endogenous levels of MAST205 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MAST2. AA range:1201-1250

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MAST2

Target: MAST2 (Microtubule Associated serine/threonine Kinase 2 (MAST2))

Alternative Name: MAST2

Background:

Synonyms: MAST2, KIAA0807, MAST205, Microtubule-associated serine/threonine-protein kinase 2

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.,PTM:Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 protein kinase domain.,subcellular location:Recruited to the sub-membranous area on interaction with PC-LKC.,tissue specificity:Abundant in the testis.,

Gene Name: MAST2

Protein Name: Microtubule-associated serine/threonine-protein kinase 2

Molecular Weight: 196 kDa

Gene ID: 23139

UniProt: Q6P0Q8