COQ8A antibody (AA 301-350)

Catalog No. ABIN1534014

This Rabbit Polyclonal antibody specifically detects COQ8A in WB, ELISA, IF and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for COQ8A antibody (AA 301-350) (ABIN1534014)

Target: COQ8A (Coenzyme Q8A (COQ8A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COQ8A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-COQ8A Antibody

Binding Specificity: AA 301-350

Purpose: CABC1 Antibody

Specificity: CABC1 Polyclonal Antibody detects endogenous levels of CABC1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ADCK3. AA range:301-350

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for COQ8A

Target: COQ8A (Coenzyme Q8A (COQ8A))

Alternative Name: ADCK3

Background:

Synonyms: ADCK3, CABC1, PP265, Chaperone activity of bc1 complex-like, mitochondrial, Chaperone-ABC1-like, aarF domain-containing protein kinase 3

Background: This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found, however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: ADCK3

Protein Name: Chaperone activity of bc1 complex-like mitochondrial

Molecular Weight: 71 kDa

Gene ID: 56997

OMIM: 606980

UniProt: Q8NI60