PCDH11X antibody (AA 531-580)

Catalog No. ABIN1534107

This Rabbit Polyclonal antibody specifically detects PCDH11X in ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PCDH11X antibody (AA 531-580) (ABIN1534107)

Target: PCDH11X (PCDH11) (Protocadherin 11 (PCDH11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH11X antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PCDH11X Antibody

Binding Specificity: AA 531-580

Purpose: Protocadherin-11 Antibody

Specificity: Protocadherin-11 Polyclonal Antibody detects endogenous levels of Protocadherin-11 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PCDH-X/Y. AA range:531-580

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PCDH11X

Target: PCDH11X (PCDH11) (Protocadherin 11 (PCDH11))

Background:

Synonyms: PCDH11Y, PCDH11, PCDH22, PCDHY, Protocadherin-11 Y-linked, Protocadherin-11, Protocadherin on the Y chromosome, PCDH-Y, Protocadherin prostate cancer, Protocadherin-PC, Protocadherin-22, PCDH11X, KIAA1326, PCDH11, PCDHX, Protocadherin-11 X-

Background: This gene belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. This gene is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013],

Gene Name: PCDH11X/PCDH11Y

Protein Name: Protocadherin-11 X/Y-linked

Molecular Weight: 146 kDa

Gene ID: 83259, 27328

OMIM: 400022

UniProt: Q9BZA8