SLK antibody (AA 1151-1200)

Catalog No. ABIN1534120

The Rabbit Polyclonal anti-SLK antibody is suitable to detect SLK in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for SLK antibody (AA 1151-1200) (ABIN1534120)

Target: SLK (STE20-Like Kinase (SLK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SLK Antibody

Binding Specificity: AA 1151-1200

Purpose: SLK Antibody

Specificity: SLK Polyclonal Antibody detects endogenous levels of SLK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SLK. AA range:1151-1200

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SLK

Target: SLK (STE20-Like Kinase (SLK))

Alternative Name: SLK

Background:

Synonyms: SLK, KIAA0204, STK2, STE20-like serine/threonine-protein kinase, STE20-like kinase, hSLK, CTCL tumor antigen se20-9, STE20-related serine/threonine-protein kinase, STE20-related kinase, Serine/threonine-protein kinase 2

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Mediates apoptosis and actin stress fiber dissolution.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Proteolytically cleaved by caspase-3.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 422.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 611.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 614.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UVR domain.,tissue specificity:Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.,

Gene Name: SLK

Protein Name: STE20-like serine/threonine-protein kinase

Molecular Weight: 142 kDa

Gene ID: 9748

UniProt: Q9H2G2