CLK4 antibody (AA 101-150)

Catalog No. ABIN1534134

This Rabbit Polyclonal antibody specifically detects CLK4 in WB, ELISA, IHC and IF. It exhibits reactivity toward Mouse and Human.

Quick Overview for CLK4 antibody (AA 101-150) (ABIN1534134)

Target: CLK4 (CDC-Like Kinase 4 (CLK4))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CLK4 Antibody

Binding Specificity: AA 101-150

Purpose: CLK4 Antibody

Specificity: CLK4 Polyclonal Antibody detects endogenous levels of CLK4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CLK4. AA range:101-150

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CLK4

Target: CLK4 (CDC-Like Kinase 4 (CLK4))

Alternative Name: CLK4

Background:

Synonyms: CLK4, Dual specificity protein kinase CLK4, CDC-like kinase 4

Background: CDC like kinase 4(CLK4) Homo sapiens The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined. [provided by RefSeq, Jul 2008],

Gene Name: CLK4

Protein Name: Dual specificity protein kinase CLK4

Molecular Weight: 57 kDa

Gene ID: 57396

OMIM: 607969

UniProt: Q9HAZ1