BRMS1 antibody (AA 21-70)

Catalog No. ABIN1534138

The Rabbit Polyclonal anti-BRMS1 antibody is suitable to detect BRMS1 in samples from Human, Rat and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for BRMS1 antibody (AA 21-70) (ABIN1534138)

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRMS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-BRMS1 Antibody

Binding Specificity: AA 21-70

Purpose: BRMS-1 Antibody

Specificity: BRMS-1 Polyclonal Antibody detects endogenous levels of BRMS-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human BRMS1. AA range:21-70

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BRMS1

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Alternative Name: BRMS1

Background:

Synonyms: BRMS1, Breast cancer metastasis-suppressor 1

Background: This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines.The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Gene Name: BRMS1

Protein Name: Breast cancer metastasis-suppressor 1

Molecular Weight: 28 kDa

Gene ID: 25855

OMIM: 606259

UniProt: Q9HCU9