DUSL2 antibody (AA 421-470)

Catalog No. ABIN1534152

This Rabbit Polyclonal antibody specifically detects DUSL2 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for DUSL2 antibody (AA 421-470) (ABIN1534152)

Target: DUSL2 (DUS2L) (Dihydrouridine Synthase 2-Like (DUS2L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-DUSL2 Antibody

Binding Specificity: AA 421-470

Purpose: DUS2L Antibody

Specificity: DUS2L Polyclonal Antibody detects endogenous levels of DUS2L protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human DUS2L. AA range:421-470

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DUSL2

Target: DUSL2 (DUS2L) (Dihydrouridine Synthase 2-Like (DUS2L))

Alternative Name: DUS2L

Background:

Synonyms: DUS2L, DUS2, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, Up-regulated in lung cancer protein 8, URLC8, tRNA-dihydrouridine synthase 2-like, hDUS2

Background: dihydrouridine synthase 2(DUS2) Homo sapiens This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012],

Gene Name: DUS2L

Protein Name: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

Molecular Weight: 55 kDa

Gene ID: 54920

OMIM: 609707

UniProt: Q9NX74